Herbal Science Research - pediatric

The effect of gender and ethnicity on children's attitudes and preferences for essential oils: a pilot study.

Site Editor — Mon, 22 Oct 2007 18:12:49 -0700

The effect of gender and ethnicity on children's attitudes and preferences for essential oils: a pilot study.: Explore (NY). 2007 Jul-Aug;3(4):378-85 Authors: Fitzgerald M, Culbert T, Finkelstein M, Green M, Johnson A, Chen S

CONTEXT: Aromatherapy is frequently recommended for children but children's preferences for specific essential oils are not well documented. OBJECTIVE: To measure preferences of school aged children for essential oils based on gender and ethnicity. DESIGN: Descriptive study measuring children's responses to and preferences for selected essential oils. SETTING: Pediatric integrative medicine clinic in a Midwestern children's hospital. PARTICIPANTS: Healthy school-age children of Latino (N = 39) and non-Latino Caucasian (NLC) (N = 48) ethnicity, 41.7% of the NLC group and 59.0% of the Latino Group were males. INTERVENTION: Participants smelled single essential oils, answered three forced choice questions and one open ended question, order of exposure was varied. OUTCOME MEASURES: Participants evaluated each scent's effect on mood and energy, stated their preferences, indicated if scents evoked particular thoughts and selected a favorite essential oil. RESULTS: Females were more likely to feel happy when smelling sweet orange (p = .043). Female Latinos were more likely than NLC females to find sweet orange calming (56.2% vs. 18.5%). Male Latinos were more likely (65.2%) to describe peppermint as "energetic" than male NLC (30%). Children chose an essential oil that they rated as "making them feel happy" (72.6%) and/or as "liking the most" (64.3%). Other results that approached statistical significance were: females felt more energetic with spearmint (p = .055). Latinos preferred spearmint over NLC (p = .075), and all males felt more energetic when smelling ginger (p = .091). Ginger and lavender were the least preferred. Results indicate that children have specific essential oil scent preferences. There is trend toward differences based on gender and ethnicity.

PMID: 17681258 [PubMed - indexed for MEDLINE]

[Time and again it hits the little ones: herbal therapy for childhood diarrhea]

Site Editor — Sun, 21 Oct 2007 05:46:49 -0700

[Time and again it hits the little ones: herbal therapy for childhood diarrhea]: Wien Med Wochenschr. 2007;157(13-14):308-11 Authors: Biller A

Acute diarrhea is amongst the most common childhood illnesses. Of paramount importance is an oral rehydration with glucose-electrolyte solutions. A number of herbal therapies are available to shorten the duration of the diarrhea and to alleviate the unpleasant symptoms. Although herbal preparations are generally well tolerated, only a few have been tested on children and adjusted to their needs. Various therapies for diarrhea in childhood are highlighted with regard to the clinical trials with children, and their user-friendliness.

PMID: 17704977 [PubMed - indexed for MEDLINE]

Phytoterapy [sic]: a glimmer of hope in the prevention of recurrent respiratory tract infections in children.

Site Editor — Sun, 21 Oct 2007 05:38:44 -0700

Phytoterapy: a glimmer of hope in the prevention of recurrent respiratory tract infections in children.: Minerva Pediatr. 2007 Aug;59(4):389-395 Authors: Miniello VL, Brunetti L, Cafagna R, Lieggi MS, Lippolis P, Natile M, Francavilla R, Armenio L

Evidence on the efficacy of standardised phytoterapic extracts for the prevention of recurrent respiratory tract infections (RRTIs) in children is reviewed. Echinacea extracts are widely used in European countries and in the United States as immune-stimulating agents. However, further prospective, appropriately powered clinical studies are required to confirm their benefits in reducing duration and severity of RRTIs.

PMID: 17947844 [PubMed - as supplied by publisher]

Environmental exposures and ADHD.

Site Editor — Thu, 04 Oct 2007 05:52:23 -0700

Environmental exposures and ADHD.: Environ Health Perspect. 2007 Aug;115(8):A398; author reply A399 Authors: Brondum J

Full-text PDF

PMID: 17687423 [PubMed - indexed for MEDLINE]

Traditional practices, beliefs and uses of medicinal plants in [...] maternal-baby health of Criollo woman in central Argentina.

Site Editor — Thu, 04 Oct 2007 05:40:04 -0700

Traditional practices, beliefs and uses of medicinal plants in relation to maternal-baby health of Criollo woman in central Argentina.: Midwifery. 2007 Sep 28; Authors: Martínez GJ

OBJECTIVE: to present information on traditional practices and medicinal uses of plants for treating health diseases related to the reproductive cycle of Criollo women living in the hills of the province of Córdoba; and to interpret these uses in the context of this population's folk medicine. DESIGN: data were collected during several field trips to the study area based on the guidelines of a research project that included ethnographic and ethnobotanical aspects of the study area. SETTING: a rural community of central Argentina. PARTICIPANTS: a total of 62 peasants were interviewed on the basis of a semi-structured system. Repeated open and extensive interviews were also undertaken with seven women who had previously worked as midwives in areas of difficult access. FINDINGS: this study found that 12 different female diseases and complaints are treated using a total of 48 plant species belonging to 27 botanical families, with 71 different medicinal uses. The traditional beliefs and practices associated with maternal-baby health care in rural areas highlights the existing combination of principles reformulated from humoral medicine, the use of analogical reasoning, and ontological and functional interpretations of morbid processes. The principle of Hypocratical opposition and hot-cold categorisation are significant criteria that rule over the practices of mother and child health care during birth and puerperium. IMPLICATIONS FOR PRACTICE: consequences of traditional knowledge on the health care of peasant women are discussed, based on the analysis of traditional practices from a peasant's point of view.

PMID: 17905491 [PubMed - as supplied by publisher]

Intake of water, herbal teas and non-breast milks during the first month of life: [...] impact on breastfeeding duration

Site Editor — Wed, 26 Sep 2007 19:09:53 -0700

Intake of water, herbal teas and non-breast milks during the first month of life: Associated factors and impact on breastfeeding duration.: Early Hum Dev. 2007 Sep 19; Authors: Giugliani ER, do Espírito Santo LC, de Oliveira LD, Aerts D

BACKGROUND:: The use of non-breast milks seems to cause more harm to the child's health than the isolated introduction of water/herbal teas. AIMS:: Study the factors associated with introduction of water/herbal teas or non-breast milks during the first month of life and determine the impact of this supplementation on breastfeeding duration. STUDY DESIGN:: Nested cross-sectional study. SUBJECTS:: 220 mother-infant pairs contacted in the maternity ward, at 7 days and at the end of 1, 2, 4, and 6 months. OUTCOME MEASURES:: Introduction of water/herbal teas or non-breast milks in the first month of life based on data collected during a home visit 30 days after delivery. RESULTS:: Introduction of water/herbal teas was associated with maternal age <20 years (prevalence ratio=1.55; 95%CI 1.14-2.09), <6 prenatal consultations (1.48; 1.09-2.01), cohabitation with maternal grandmother (1.51; 1.10-2.10), and poor latch-on at 30 days (1.87; 1.35-2.58). Introduction of non-breast milks was associated with breastfeeding of previous children for <6 months (3.18; 1.18-8.58), cesarean (1.92; 1.07-3.44), poor latch-on at 30 days (2.82; 1.55-5.11), use of pacifier at 7 days (2.75; 1.38-5.48), introduction of herbal teas in the first 7 days (2.75; 1.15-4.15) and breast engorgement at 7 days (2.19; 1.01-3.16). Introduction of non-breast milks negatively influenced breastfeeding duration (p<0.001); this was not observed with water/herbal teas (p=0.277). CONCLUSION:: Priority should be given to preventing the early introduction on non-breast milks, especially in mother-infant pairs with associated risk factors.

PMID: 17888592 [PubMed - as supplied by publisher]

Pediatric toxicology.

Site Editor — Fri, 13 Jul 2007 17:57:04 -0700

Pediatric toxicology.: Emerg Med Clin North Am. 2007 May;25(2):283-308; abstract vii-viii Authors: Eldridge DL, Van Eyk J, Kornegay C

Pediatric patients present unique concerns in the field of medical toxicology. First, there are medicines that are potentially dangerous to small children, even when they are exposed to very small amounts. Clinicians should be wary of these drugs even when young patients present with accidental ingestions of apparently insignificant amounts. Next, over-the-counter laxatives and syrup of ipecac, although not commonly considered abused substances, may be misused in both the setting of Munchausen's syndrome by proxy and in adolescents who have eating disorders. Their use should be considered in any gastrointestinal illness of uncertain origin. Finally, as the use of syrup of ipecac at home now has been discouraged by many, some have explored using activated charcoal at home as a new method of prehospital gastrointestinal decontamination. The literature examining activated charcoal and its use in this capacity is discussed.

PMID: 17482021 [PubMed - indexed for MEDLINE]

Pelargonium sidoides preparation (EPs 7630) in the treatment of acute bronchitis in adults and children.

Site Editor — Fri, 25 May 2007 02:33:32 -0700

Pelargonium sidoides preparation (EPs 7630) in the treatment of acute bronchitis in adults and children.: Phytomedicine. 2007;14 Suppl 6:69-73 Authors: Matthys H, Kamin W, Funk P, Heger M

Acute bronchitis, although mostly caused by viral infections, is commonly treated with antibiotics. As antibiotics should only be prescribed upon strict indication, treatment options like a liquid herbal drug preparation from the roots of Pelargonium sidoides (EPs 7630) gain more and more interest. To evaluate the efficacy and safety of treatment with EPs 7630 in patients with acute bronchitis, a multi-centre, prospective, open observational study was conducted in 440 study sites located in Germany. A total of 2099 patients aged 0-93 years with productive cough for less than six days without indication for treatment with antibiotics were given EPs 7630-solution in an age-dependent dosage for 14 days. The primary outcome criterion was the mean change of the Bronchitis Severity Score (BSS: cough, sputum, rales/rhonchi, chest pain at cough, dyspnoea) from baseline to patient's individual last observation. During treatment, the mean BSS of all patients decreased from 7.1+/-2.9 points at baseline to 1.0+/-1.9 points at patients' individual last visit. Subgroup analysis for children showed a decrease of mean BSS from 6.3+/-2.8 points to 0.9+/-1.8 points and analysis of children younger than three years showed a decrease of mean BSS from 5.2+/-2.5 points to 1.2+/-2.1 points. Adverse events occurred in 26/2099 (1.2%) patients. Serious adverse events were not reported. In conclusion, EPs 7630 is an effective and well tolerated treatment of acute bronchitis in adults, children and infants outside the strict indication for antibiotic treatment.

Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls.

Site Editor — Fri, 11 May 2007 16:18:53 -0700

Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls.: Environ Health Perspect. 2007 Jan;115(1):116-21 Authors: Wolff MS, Teitelbaum SL, Windham G, Pinney SM, Britton JA, Chelimo C, Godbold J, Biro F, Kushi LH, Pfeiffer CM, Calafat AM

BACKGROUND: Hormonally active environmental agents have been measured among U.S. children using exposure biomarkers in urine. However, little is known about their variation by race, age, sex, and geography, and no data exist for newly developed biomarkers. OBJECTIVE: Our goal was to characterize relevant, prevalent exposures for a study of female pubertal development. METHODS: In a pilot study among 90 girls from New York City, New York, Cincinnati, Ohio, and northern California, we measured 25 urinary analytes representing 22 separate agents from three chemical families: phytoestrogens, phthalates, and phenols. Exposures occur chiefly from the diet and from household or personal care products. RESULTS: Participants represented four racial/ethnic groups (Asian, black, Hispanic, white), with mean age of 7.77 years. Most analytes were detectable in > 94% of samples. The highest median concentrations for individual analytes in each family were for enterolactone (298 microg/L), monoethylphthalate (MEP; 83.2 microg/L), and benzophenone-3 (BP3; 14.7 microg/L). Few or no data have been reported previously for four metabolites: mono(2-ethyl-5-carboxypentyl) phthalate, tridosan, bisphenol A (BPA), and BP3; these were detected in 67-100% of samples with medians of 1.8-53.2 microg/L. After multivariate adjustment, two analytes, enterolactone and BPA, were higher among girls with body mass index < 85th reference percentile than those at or above the 85th percentile. Three phthalate metabolites differed by race/ethnicity [MEP, mono(2-ethylhexyl) phthalate, and mono-3-carboxypropylphthalate]. CONCLUSIONS: A wide spectrum of hormonally active exposure biomarkers were detectable and variable among young girls, with high maximal concentrations (> 1,000 microg/L) found for several analytes. They varied by characteristics that may be relevant to development.

[Alternative therapy in childhood cancer]

Site Editor — Fri, 11 May 2007 15:39:11 -0700

[Alternative therapy in childhood cancer]: Orv Hetil. 2006 Oct 8;147(40):1945-9 Authors: Szirmai H, Földesi E, Zsámbor C, Hauser P, Jakab Z, Müller J, Schuler D, Garami M

INTRODUCTION: In Hungary there are as many as 300 children diagnosed with malignant tumor each year. Along with the traditional treatments, alternative remedies have been increasingly applied in the past two decades despite the availability of the more complex and more effective malignant tumor treatments. AIMS: The authors attempted to find out about the applied alternative remedies for childhood cancer outside the traditional treatments, to determine how frequently they were applied and to examine what psychological factors had lead to their application. PATIENTS: Children's parents, getting active treatment and also the ones that have been rehabilitated at the II. Department of Pediatrics, Semmelweis University. RESULTS: 60 percent of the 34 children being examined were getting several kinds of therapy. The most frequently applied alternative remedies were the following: nature products, diet supplements, herbs, diet changes. The parents' choice was mainly influenced by other parents' opinions (42%), frequently appearing commercials in media (26%) and their current financial background (23%). The authors have found on the base of their research that the general aim of parents was: to help their own incapability to help (31%), to make sure about the efficiency of the treatment (45%). CONSEQUENCES: Independently of demographic or clinical facts the use of alternative remedies are excessively widespread and popular with children having tumor. Thus it is not advisable or reasonable to absolutely refuse them since they are quite widespread and people tend to strongly believe in them. As for doctors, they are to give professional advice and help with choosing the alternative remedies that are not harmful or even more, the ones that can make traditional treatments more effective.

A comparison of botanical and synthetic substances commonly used to prevent head lice...infestation

Site Editor — Fri, 11 May 2007 15:32:54 -0700

A comparison of botanical and synthetic substances commonly used to prevent head lice (Pediculus humanus var. capitis) infestation.: Int J Dermatol. 2007 Apr;46(4):422-6 Authors: Canyon DV, Speare R

Background Pediculosis, caused by head lice (Pediculidae: Pediculus humanus var. capitis), is experiencing a global resurgence, with the prevalence in primary schools averaging as high as 40% in some areas regardless of socioeconomic factors. Control efforts using chemical treatments are becoming increasingly ineffective, with insecticide resistance recorded in several countries. Prevention using repellents and oils would be useful if they limited transmission. Many commercially available substances reputedly have effective repellent qualities, but remain untested. Methods This study tested the preventative efficacy of N,N-diethyl-3-methylbenzamide (DEET) against several commercially available botanicals to clarify their value as transmission inhibitors, irritants, repellents, and antifeedants. Results The transfer of head lice to treated hairs was limited by the slippery nature of the oils rather than their repellent qualities. Irritancy was not important because lice proceeded despite being highly irritated, except in the case of coconut. Tea tree and peppermint caused the most repellence, and tea tree and lavender prevented some blood feeding on treated skin. Comparatively, tea tree oil was most efficacious, with DEET ranking equal second overall with coconut, peppermint, and a botanical mixture. Conclusions Neither DEET nor any of the botanicals tested showed sufficient preventative efficacy to be endorsed.

Successful treatment of pediatric psoriasis with Indigo naturalis composite ointment.

Site Editor — Thu, 01 Feb 2007 16:39:27 -0800

Successful treatment of pediatric psoriasis with Indigo naturalis composite ointment.: Pediatr Dermatol. 2006 Sep-Oct;23(5):507-10 Authors: Lin YK, Yen HR, Wong WR, Yang SH, Pang JH

The treatment of psoriasis in children is still an intractable problem and demands a long-term therapy with prolonged efficacy that is free from serious adverse events. Many modes of therapy are currently in use but the disease is often resistant to treatment owing to the unacceptable toxicity that leads to poor compliance. Therefore, to develop an alternative treatment is indispensable. Traditional Chinese medicine has been documented for over 1000 years to provide various effective treatments for inflammatory skin diseases. Herein, we report an 8-year-old boy with recalcitrant pediatric psoriasis who, after multiple treatment failures with conventional antipsoriatic medications, showed remarkable clinical improvement with 8 weeks of topical treatment with Indigo naturalis composite ointment. Remission has lasted for over 2 years until now. Our patient's response suggests that topical Indigo naturalis composite ointment may provide a safe and effective alternative treatment for pediatric psoriasis.

Sublingual immunotherapy with a latex extract in paediatric patients: a double-blind, placebo-controlled study.

Site Editor — Thu, 01 Feb 2007 16:30:25 -0800

Sublingual immunotherapy with a latex extract in paediatric patients: a double-blind, placebo-controlled study.: Curr Med Res Opin. 2006 Aug;22(8):1515-22 Authors: Bernardini R, Campodonico P, Burastero S, Azzari C, Novembre E, Pucci N, Massai C, De Martino M, Vierucci A

BACKGROUND: Natural rubber latex (NRL) allergy remains an important allergic disease triggering urticaria, asthma, angioedema and anaphylaxis. Specific immunotherapy can help to solve problems related to NRL allergy. So far, no controlled clinical trials have been performed in children suffering from NRL allergy. OBJECTIVES: To evaluate the safety and efficacy of sublingual immunotherapy (SLIT) with a commercial NRL extract in children with NRL allergy. RESEARCH DESIGN: Randomized, double-blind, placebo-controlled, 12-month trial. PATIENTS AND METHODS: Twenty-six children (aged 4-15 years) with NRL allergy, who had cutaneous and/or respiratory symptoms, including oral allergy syndrome to fruits containing cross-reactive allergens, were recruited. Twelve children were randomized to SLIT with a commercial NRL extract and eight to placebo (3:2). An additional six children with NRL allergy served as untreated controls. MAIN OUTCOMES MEASURES: A glove use test was utilized to monitor skin and systemic symptoms triggered by NRL exposure at baseline and 3, 6, 9 and 12 months later. Oral allergy symptoms were also monitored. RESULTS: No side effects related to treatments were observed in any patient. A significant improvement of symptom score in treated patients in comparison with baseline values was observed at 3 months (p = 0.01) and consolidated after 1 year of treatment (p = 0.0005). In comparison with placebo, significant improvements were observed starting at 9 months from study start (p = 0.015) and at 12 months (p = 0.005). The number of foods triggering oral allergy symptoms increased in placebo and control subjects, but not in active treated patients (p = 0.05). CONCLUSION: Latex SLIT was safe and efficacious in paediatric patients with NRL allergy.

Complementary and alternative medicine use in pediatric oncology patients in eastern Turkey.

Site Editor — Sat, 20 Jan 2007 16:35:43 -0800

Complementary and alternative medicine use in pediatric oncology patients in eastern Turkey.: Cancer Nurs. 2007 Jan-Feb; 30(1): 38-44
Gözüm S, Arikan D, Büyükavci M

The use of complementary and alternative medicines (CAM) among children with cancer is becoming increasingly popular. Therefore, it is important to gain insight into the prevalence and factors related to the use of CAM. This study presents findings from a study of parents of 88 children with cancer who were receiving or had received conventional therapy for treatment of childhood cancer at a pediatric oncology unit in eastern Turkey. The findings indicated that 48.9% of the respondents reported the use of 1 or more CAM therapies. The most commonly used modality was herbal products such as herbal tea and herbal meal, mostly stinging nettle (Urtica dioica). The findings of this study indicate that CAM users were children who were an average of 3 years older than nonuser children and that CAM use was more prevalent among the children who had been diagnosed with cancer for a longer time than nonusers. There were no significant difference between users and nonusers regarding sociodemographic characteristics (such as age education level, economic status), hopelessness score of parents, gender of child, and treatment status. Healthcare providers should remain informed about the benefits and adverse effects of complementary and alternative therapies to discuss treatment options with patients and their families and to monitor treatment efficacy.

Sunflower therapy for children with specific learning difficulties (dyslexia): A randomised, controlled trial.

Site Editor — Sat, 13 Jan 2007 21:32:13 -0800

Sunflower therapy for children with specific learning difficulties (dyslexia): A randomised, controlled trial.: Complement Ther Clin Pract. 2007 Feb; 13(1): 15-24 Bull L

The aim of the study was to determine the clinical and perceived effectiveness of the Sunflower therapy in the treatment of childhood dyslexia. The Sunflower therapy includes applied kinesiology, physical manipulation, massage, homeopathy, herbal remedies and neuro-linguistic programming. A multi-centred, randomised controlled trial was undertaken with 70 dyslexic children aged 6-13 years. The research study aimed to test the research hypothesis that dyslexic children 'feel better' and 'perform better' as a result of treatment by the Sunflower therapy. Children in the treatment group and the control group were assessed using a battery of standardised cognitive, Literacy and self-esteem tests before and after the intervention. Parents of children in the treatment group gave feedback on their experience of the Sunflower therapy. Test scores were compared using the Mann Whitney, and Wilcoxon statistical tests. While both groups of children improved in some of their test scores over time, there were no statistically significant improvements in cognitive or Literacy test performance associated with the treatment. However, there were statistically significant improvements in academic self-esteem, and reading self-esteem, for the treatment group. The majority of parents (57.13%) felt that the Sunflower therapy was effective in the treatment of learning difficulties. Further research is required to verify these findings, and should include a control group receiving a dummy treatment to exclude placebo effects.

Clinical efficacy and safety of sublingual immunotherapy with tree pollen extract in children.

Site Editor — Sat, 06 Jan 2007 00:02:29 -0800

Clinical efficacy and safety of sublingual immunotherapy with tree pollen extract in children.: Allergy. 2006 Oct;61(10):1177-83 Authors: Valovirta E, Jacobsen L, Ljørring C, Koivikko A, Savolainen J

BACKGROUND: Subcutaneous immunotherapy has been the principal approach of immunotherapy in the treatment of allergic diseases. Several clinical studies with birch, alder or hazel pollen extract conducted as subcutaneous immunotherapy have been published suggesting a well-tolerated and clinically effective treatment. Only a few clinical studies of sublingual immunotherapy (SLIT) with these allergens have been published. This study investigated the clinical efficacy, safety and dose-response relationship of SLIT in children suffering from rhinoconjunctivitis with/without asthma. METHODS: Eighty-eight children (5-15 years) with a history of tree pollen-induced allergic rhinoconjunctivitis with/without seasonal asthma for >or=2 years were included. Allergy to tree pollen was confirmed by positive skin-prick test, positive specific IgE and positive conjunctival provocation test. The extract used was a glycerinated mixture of Betula verrucosa, Corylus avellana and Alnus glutinosa 100,000 SQ-U/ml. Children were randomized into three groups receiving SLIT 5 days a week for up to 18 months; dose group 1: accumulated weekly dose of 24,000 SQ-U; dose group 2: accumulated weekly dose of 200,000 SQ-U; and placebo. RESULTS: In the birch pollen season, dose group 2 showed a significant reduction of symptom (P = 0.01) and medication scores (P = 0.04) compared with placebo. Dose group 1 showed a significant reduction of symptom scores (P = 0.03). There were no statistical differences between dose groups 1 and 2. All children tolerated the treatment well. CONCLUSION: SLIT with tree pollen extract provided dose-dependent benefits in tree pollen-allergic children in terms of significantly reduced symptoms and medication use. The treatment was well tolerated.

Treatment of ADHD with French maritime pine bark extract, Pycnogenol.

Site Editor — Thu, 04 Jan 2007 17:42:46 -0800

Treatment of ADHD with French maritime pine bark extract, Pycnogenol.: Eur Child Adolesc Psychiatry. 2006 Sep;15(6):329-35 Authors: Trebatická J, Kopasová S, Hradecná Z, Cinovský K, Skodácek I, Suba J, Muchová J, Zitnanová I, Waczulíková I, Rohdewald P, Duracková Z

Attention Deficit/Hyperactivity Disorder (ADHD) is the most common psychiatric disorder in children. Pycnogenol, an extract from the bark of the French maritime pine, consisting of phenolic acids, catechin, taxifolin and procyanidins, has shown improvement of ADHD in case reports and in an open study. Aim of the present study was to evaluate the effect of Pycnogenol on ADHD symptoms. Sixty-one children were supplemented with 1 mg/kg/day Pycnogenol or placebo over a period of 4 weeks in a randomised, placebo-controlled, doubleblind study. Patients were examined at start of trial, 1 month after treatment and 1 month after end of treatment period by standard questionnaires: CAP (Child Attention Problems) teacher rating scale, Conner's Teacher Rating Scale (CTRS), the Conner's Parent Rating Scale (CPRS) and a modified Wechsler Intelligence Scale for children. Results show that 1-month Pycnogenol administration caused a significant reduction of hyperactivity, improves attention and visual-motoric coordination and concentration of children with ADHD. In the placebo group no positive effects were found. One month after termination of Pycnogenol administration a relapse of symptoms was noted. Our results point to an option to use Pycnogenol as a natural supplement to relieve ADHD symptoms of children.

Survey...by Kansas and Wisconsin WIC Participants Reveals Moderate, Appropriate Use and Identifies Herbal Education Needs.

Site Editor — Fri, 09 Jun 2006 04:36:02 -0700

Survey of Herbal Use by Kansas and Wisconsin WIC Participants Reveals Moderate, Appropriate Use and Identifies Herbal Education Needs.: J Am Diet Assoc. 2006 Feb;106(2):227-37 Authors: Lohse B, Stotts JL, Priebe JR

OBJECTIVE: To examine herbal use by a sample of low-income, nutritionally vulnerable children. DESIGN: Caregivers completed a survey of child and caregiver herbal usage practices. SUBJECTS/SETTING: A convenience sample of 2,562 caregivers to children participating in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) in Kansas and Wisconsin who were attending a WIC clinic was selected. WIC project selection was random, with stratification for geographic and ethnic representation. STATISTICAL ANALYSES PERFORMED: Herbal usage profiles were described with measures of central tendency. Groups were compared with a two-tailed independent t test and chi(2) for continuous and categorical variables, respectively. RESULTS: Child herbal use was reported on 917 surveys, representing 1,363 children ranging in age from 1 week to 17.5 years; 820 were younger than age 5 years. Herb use was greater among Latino children (48.4% vs 31.4%) and caregivers (43.4% vs 37.2%). Caregivers had a mean age of 27.8+/-8.32 years and 38.8% (n=994) denoted using herbs. Herbs most commonly used by children were aloe vera, chamomile, garlic, peppermint, lavender, cranberry, ginger, echinacea, and lemon. Reasons for herbal use paralleled recommendations. Family (78.9%) and friends (32.9%) were predominant information sources. Herbs with safety issues, such as St John's wort, dong quai, and kava were used. Herbal use characteristics did not differ between states, but were unique for Latino clients. CONCLUSIONS: Herbal use by WIC children is mostly congruent with known indications; however, practices with potential to harm urge herbal education in WIC clinics, especially for Latinos.

Views of pediatric health care providers on the use of herbs and dietary supplements in children.

Site Editor — Fri, 09 Jun 2006 04:30:52 -0700

Views of pediatric health care providers on the use of herbs and dietary supplements in children.: Clin Pediatr (Phila). 2005 Sep;44(7):579-87 Authors: Woolf AD, Gardiner P, Whelan J, Alpert HR, Dvorkin L

Herbs and dietary supplements (HDS) are widely used by adults for treating illnesses and/or preserving good health, and many parents use HDS for their children as well. Previous reports suggest parents will not divulge HDS use to health care providers for fear of their skepticism or disapproval. Yet the views of pediatric health care providers on HDS use in children are not well known. This study investigated the attitudes and practices of pediatric nurses and physicians regarding HDS use in children, in order to identify those characteristics associated with a high degree of confidence in initiating a dialogue on the topic of HDS with families in their practice. A written survey on attitudes and practices toward HDS was developed, piloted, revised, and then administered to a convenience sample of practitioners attending a regional postgraduate course in general pediatrics. Only 42% of 204 pediatric health care providers sampled felt confident in initiating discussions about the therapeutic use of herbs and dietary supplements with families in their practice. Confidence in discussing HDS with families correlated with both personal use of an HDS (OR 3.22; p=0.033) and length of time in practice less than 10 years (OR 8.26; p=0.007). Less than 18% felt that HDS were safe for children under 6 months of age; and only 35% felt they were safe for use in children < 24 months old. Only 7% felt that parents should be allowed to give their hospitalized child an herb or dietary supplement they had brought with them from home, although this increased to 35% if the herb or dietary supplement had been prescribed by a physician. Ninety-two percent of practitioners thought that HDS should be more closely regulated by the FDA. Only a minority of pediatric community practitioners felt confident in discussing HDS with families of children in their practice. Those who had been in practice for a shorter time and who had used HDS themselves were more likely to report confidence in initiating such discussions. The provision of more postgraduate educational opportunities to learn about herbs and dietary supplements may alleviate some practitioners' concerns about their own competency in discussing HDS with families in their practice.

Science for All: Pay Attention! Focusing on ADHD (HHS Only)

Site Editor — Fri, 09 Jun 2006 04:12:49 -0700

Science for All: Pay Attention! Focusing on ADHD (HHS Only)

Presented by: Staff Training in Extramural Programs

Aired date: 1/10/2006 2:47:00 PM Eastern Time

Parental use of the term "Hot Qi" to describe symptoms in their children in Hong Kong: a cross sectional survey.

Site Editor — Fri, 09 Jun 2006 04:02:33 -0700

Parental use of the term "Hot Qi" to describe symptoms in their children in Hong Kong: a cross sectional survey.: J Ethnobiol Ethnomedicine. 2006 Jan 5;2(1):2 Authors: Kong FY, Ng DK, Chan CH, Yu WL, Chan D, Kwok KL, Chow PY

ABSTRACT: BACKGROUND: The Chinese term "Hot Qi" is often used by parents to describe symptoms in their children. The current study was carried out to estimate the prevalence of using the Chinese term "Hot Qi" to describe symptoms in children by their parents and the symptomatology of "Hot Qi". METHOD: A cross sectional survey by face-to-face interview with a semi-structured questionnaire was carried out in a public hospital and a private clinic in Hong Kong. The parental use of the term "Hot Qi", the symptoms of "Hot Qi" and the remedies used for "Hot Qi" were asked. RESULTS: 1060 pairs of children and parents were interviewed. 903 (85.1%) of parents claimed that they had employed the term "Hot Qi" to describe their children's symptoms. Age of children and place of birth of parents were the predictors of parents using the term "Hot Qi". Eye discharge (37.2%), sore throat (33.9%), halitosis(32.8%), constipation(31.0%), and irritable (21.2%) were the top five symptoms of "Hot Qi" in children. The top five remedies for "Hot Qi" were the increased consumption of water (86.8%), fruit (72.5%), soup (70.5%), and the use of herbal beverages "five-flower- tea" (a combination of several flowers such as Chrysanthemum morifolii, Lonicera japonica, Bombax malabaricum, Sophora japonica, and Plumeria rubra) (57.6%) or selfheal fruit spike (Prunella vulgaris) (42.4%). CONCLUSION: "Hot Qi" is often used by Chinese parents to describe symptoms in their children in Hong Kong. Place of birth of parents and age of the children are main factors for parents to apply the term "Hot Qi" to describe symptoms of their children. The common symptoms of "Hot Qi" suggest infections or allergy.

Clinical trial of herbal formula on weight loss in obese Korean children.

Site Editor — Fri, 09 Jun 2006 04:01:13 -0700

Clinical trial of herbal formula on weight loss in obese Korean children.: Am J Chin Med. 2005;33(5):713-22 Authors: Yoo JH, Lee EJ, Kwak CK, Sohn EH, Koh BH, Song IB, Lee KS

A traditional Korean herbal formula (KH), which is based on Taeumjowi-tang, is currently the most widely used herbal formula in Korea. In this study, KH was administered to obese children for 30 days, and was found to be clinically safe and effective. The subjects were children admitted to hospital to be treated for obesity with relative body weights (%RBW) of 20% or more. Originally, there were 31 subjects, but nine dropped out during the experiment. There were eight girls and 14 boys, whose average age was 11.00 +/- 2.62 years, average weight was 53.37 +/- 17.29 kg, and average period (30-day amount) of KH dosage was 51.18 +/- 22.58 days. The short-term effects of KH on obese children were the reduction of their BMI from 24.34 +/- 3.10 to 23.26 +/- 3.00 kg/m2, of %RBW from 34.41 +/- 10.90 to 25.94 +/- 11.18% (p < 0.01), of body fat mass from 17.99 +/- 5.37 to 16.50 +/- 4.82 kg, and of body fat from 34.16 +/- 3.75 to 32.08 +/- 3.15% (p < 0.01). Concerning anthropometrical measurements, abdominal skin-fold decreased from 26.16 +/- 9.08 to 22.90 +/- 8.35 mm, as did subscapular skin-fold from 20.86 +/- 5.20 to 18.46 +/- 5.31 mm (p < 0.01). In terms of serum lipid levels, which are indices of heart disease, their total cholesterol decreased from 195.38 +/- 31.39 to 183.25 +/- 33.27 mg/dl, the arteriosclerosis index from 4.100 +/- 0.81 to 3.84 +/- 0.64 mg/dl (p < 0.05), and serum leptin level from 14.91 +/- 6.59 to 12.24 +/- 4.98 ng/ml (p < 0.01). Concerning the safety of KH, there were no significant changes in the subjects' livers, hearts, or kidneys. Nor were there any short-term signs of clinically serious side effects or withdrawal symptoms observed. The short-term effects of KH on obese children are weight loss and a decrease in obesity.

Complementary and alternative medicine for upper respiratory tract infection in children.

Site Editor — Fri, 09 Jun 2006 03:58:07 -0700

Complementary and alternative medicine for upper-respiratory-tract infection in children.: Am J Health Syst Pharm. 2006 Jan 1; 63(1): 33-9 Carr RR, Nahata MC

PURPOSE: Evidence on the efficacy and safety of complementary and alternative medicine (CAM) for the prevention and treatment of upper-respiratory-tract infection (URTI) in children is reviewed. SUMMARY: A search of the literature to June 2005 identified six clinical trials examining the use of herbal medicines and nine trials of other CAM therapies. All articles were critically evaluated for adherence to standards of efficacy and safety research. Echinacea did not reduce the duration and severity of URTI. Andrographis paniculata or echinacea decreased nasal secretions (p < 0.01) but not URTI symptoms. A combination of echinacea, propolis, and ascorbic acid decreased the number of URTI episodes, the duration of symptoms, and the number of days of illness (p < 0.001). Echinacea was associated with a higher frequency of rash compared with placebo (p = 0.008). Neither ascorbic acid nor homeopathy was effective. The efficacy of zinc was not clear, and zinc may be associated with adverse effects in children. Osteopathic manipulation decreased episodes of acute otitis media (p = 0.04) and the need for tympanostomy tube insertion (p = 0.03) in children with recurrent acute otitis media. Stress-management therapy reduced the duration of URTI compared with relaxation therapy with guided imagery or standard care (p < 0.05). CONCLUSION: Current data are generally inadequate to support CAM for the prevention or treatment of URTI in children.

A selection of international nutritional & herbal remedies for breastfeeding concerns.

Site Editor — Fri, 09 Jun 2006 03:15:18 -0700

A selection of international nutritional & herbal remedies for breastfeeding concerns.: Midwifery Today Int Midwife. 2005;(75):38-9 Authors: Scott CR, Jacobson H